(R)-1-AZABICYCLO[2,2,2]OCTAN-3-AMINE DIHYDROCHLORIDE

(R)-1-AZABICYCLO[2,2,2]OCTAN-3-AMINE DIHYDROCHLORIDE - Names and Identifiers

Name	(R)-(+)-3-aminoquinuclidine dihydro-chloride
Synonyms	(R)-(+)-3-Aminoquinuclidine2HCl (R)-(+)-3-Aminoquinuclidine diHCl (3R)-1-azabicyclo[2.2.2]octan-3-amine (R) 3-AMINOQUINUCLIDINE HYDROCHLORIDE (R)-3-Aminoquinuclidine dihydrochloride (3R)-QUINUCLIDIN-3-AMINE DIHYDROCHLORIDE (R)-(+)-3-AMINOQUINUCLIDINE DIHYDROCHLORIDE (R)-(+)-3-aminoquinuclidine dihydro-chloride (R)-1-AZABICYCLO[2,2,2]OCTAN-3-AMINE DIHYDROCHLORIDE 1-azabicyclo[2,2,2]octan-3-amine,dihydrochloride,(R)-
CAS	123536-14-1
InChI	InChI=1/C7H14N2/c8-7-5-9-3-1-6(7)2-4-9/h6-7H,1-5,8H2/t7-/m0/s1

(R)-1-AZABICYCLO[2,2,2]OCTAN-3-AMINE DIHYDROCHLORIDE - Physico-chemical Properties

Molecular Formula	C7H16Cl2N2
Molar Mass	199.12
Density	1.06g/cm³
Melting Point	>300°C(lit.)
Boling Point	165.9°C at 760 mmHg
Specific Rotation(α)	24 º (c=1, H2O)
Flash Point	51.1°C
Solubility	DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, Heated, Sonicated), Wat
Vapor Presure	1.83mmHg at 25°C
Appearance	White to Beige Powder
Color	White to beige
Storage Condition	Inert atmosphere,Room Temperature
Stability	Hygroscopic
Refractive Index	1.551
Physical and Chemical Properties	Melting point> 300°C(lit.) specific optical rotation 24 ° (c = 1, H2O)

(R)-1-AZABICYCLO[2,2,2]OCTAN-3-AMINE DIHYDROCHLORIDE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S38 - In case of insufficient ventilation, wear suitable respiratory equipment. S36 - Wear suitable protective clothing.
WGK Germany	3
HS Code	29333990

(R)-1-AZABICYCLO[2,2,2]OCTAN-3-AMINE DIHYDROCHLORIDE - Introduction

R-3-aminoquinuclidine dihydrochloride is an organic compound with the chemical formula C20H24N2O2. 2HCl, also known as the dihydrochloride salt of aminoquinine. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
R-3-Aminoquinuclidine dihydrochloride is a white to pale yellow solid, soluble in water and alcoholic solvents. It is an optical isomer and is one of the active ingredients of aminoquinine.

Use:
R-3-aminoquinuclidine dihydrochloride has a wide range of applications in the pharmaceutical field. It is an important antimalarial drug that can be used to prevent and treat malaria. In addition, the compound is also used as an intermediate for sedatives and antibacterial drugs.

Preparation Method:
The preparation of R-3-aminoquinuclidine dihydrochloride is usually achieved by chemical synthesis methods. One commonly used method of preparation is the reaction of aminoquinine with hydrochloric acid to form the hydrochloride salt of R-3-aminoquinine.

Safety Information:
When handling R-3-aminoquinuclidine dihydrochloride, appropriate personal protective measures, such as wearing protective glasses and gloves, are required. Avoid direct contact with skin and inhalation of gas or dust. At the same time, it should be stored in a dry, well-ventilated place, away from fire and flammable materials. If required, waste should be disposed of in accordance with local regulations and practices.

Last Update：2024-04-09 21:11:58